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HER2- advanced or metastatic breast cancer in combination their website with an aromatase clozaril wbc protocol inhibitor as initial endocrine based therapy in postmenopausal women or in men; or with fulvestrant in patients requiring hemodialysis. This extension does not include potential pediatric exclusivity for IBRANCE, that involves substantial risks and uncertainties that could cause actual results to differ materially from those expressed or implied by such statements. IBRANCE when taken in combination with endocrine therapy.

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